TUESDAY, Oct. 25 (HealthDay News) -- In "Trouble,"
a cut from her 1997 Grammy-nominated album A Few Small
Repairs, pop-folk singer/songwriter Shawn Colvin captures
the kind of leaden emotions that can grab a person and not let
go. "Now I know the business of the heart/," she
sings, "And it'll get you anyway it can/You need someone to
walk with in the dark, well,/I'm your man." For most of her
47 years, Colvin said, she's been battling against depression's
darkness, first experienced as far back as childhood but only
diagnosed and treated when she was 19. "I've dealt with it
on and off since then, and began treatment in earnest again in
1989," said Colvin, who's taken home three Grammys in her
career so far -- once in 1991 for Best Contemporary Folk Album (Steady
On), then twice in 1998, when she won Record and Song of the
Year for the hit Sunny Came Home -- a song centered on a
heroine who burns down her own house, determined to start again,
"out there on her own."
Luckily for Colvin, fighting depression hasn't involved
anything nearly so dramatic. "Drugs have improved vastly
since I was 19 and I've tried several -- the one I'm using now
that works really well for me is Wellbutrin XL. I take it once a
day, it's simple," said the singer, who was born in
Carbondale, Ill., but has called Austin, Texas, home for the
past 10 years. She lives there with her 7-year-old daughter,
Caledonia. According to Colvin, being an artist has played a big
role in her decision to speak out about depression. "I
think there's a misconception that if one is an artist and, like
myself, sings sad or sensitive material, that you're risking
losing that if you treat depression," she said. "But
when I've been seriously biologically depressed I'm actually
unable to do anything."
"In fact, being treated for depression restores
me to be able to do what I do," Colvin explained. "So,
for people who are familiar with my music and like it, they
should know that 90 percent of my recorded work has been done
while I've been taking medicine for depression."
The singer's experience rang true for depression expert Dr.
Norman Sussman, a professor of psychiatry at New York University
School of Medicine. "There are some people who are so
depressed they can't bring themselves to do anything -- shower,
take out the garbage, things like that. They may sleep all the
time," he said. For others, the signs of depression may be
more subtle, including a general disinterest in activities they
used to love, an increase in morbid thoughts of death or
suicide, or an exaggerated sense of guilt over one's actions.
"The key is that it persists -- in terms of the official
criteria, it has to be there for at least two weeks,
consistently, every day," Sussman said. According to
experts, more than 14 million U.S. adults are affected by major
depressive disorder each year. Sussman said too many Americans
still mistake depression for something else -- just a temporary
"funk" or even physical illness. "Many have
trouble accepting the fact that it's primarily a biological
problem," he said. "But it is biological -- it's as if
you've got the gene for diabetes or hypertension. It just hits
you." Colvin agreed, noting that specific life events --
good or bad -- typically had little influence on when depression
stuck. And while she believes that non-drug treatments such as
therapy, diet and exercise can be helpful, pharmaceutical
intervention was the only thing that worked for her. "If
you're in a biological depression, you can diet and exercise and
take vitamins all you want, and it's not going to impact
it," she said.
According to Sussman, Colvin's medication of choice,
Wellbutrin XL, resets the balance of two important
neurochemicals linked to depression, dopamine and norepinephrine.
It's in a different class of antidepressants than the widely
used selective serotonin reuptake inhibitors (SSRIs), which work
on another powerful brain chemical, serotonin, and include drugs
such as Prozac, Paxil and Zoloft. But while Wellbutrin XL has
worked best for Colvin, "no drug is right for every
person," she said. "This drug that I'm taking may be
great for me, but it may not be for someone else." She and
most experts agree that patients may want to try different
medications, settling on the one that's best for them. The key
is for affected individuals to recognize depression's symptoms,
and then act. "It's just not something to toy with,"
said Colvin, whose next album is set for release late this year
or early in 2006. "If you're feeling bad for a prolonged
period of time, check it out -- don't suffer."